Layton And Claire - Professor Layton And The Lost Future
You may not think of the Professor Layton games as tear-jerkers, but the short-lived reunion between Layton and his lost love Claire definitely qualifies. After traveling through time and saving London, the Professor is finally reunited with Claire. She had been accidentally transported into the future 10 years, and Layton thought she was dead. However, their time together is all too brief, as Claire's body is trying to return to her own time, where she died in an explosion. The scene is made all the more memorable by Layton removing his hat, the first time in the series he does so.